What is kernicterus in medicine?

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Global Kernicterus Treatment Market
February 27, 2023 / By databridge12

What does the kernicterus treatment market mean?

Untreated jaundice in infants can result in the rare but dangerous consequence of kernicterus. Excess bilirubin harms the brain or central nervous system, which is the cause of the condition.

Jaundice affects 60 to 80 percent of newborns worldwide. In wealthy countries, only 0.4 to 2.7 out of every 100,000 children get kernicterus or acute bilirubin encephalopathy. When bilirubin levels rise to this point, they spread to the brain and damage the CNS’s tissues. At the moment, “kernicterus” describes severe neurological damage brought on by jaundice. Nonetheless, any damage brought on by severe jaundice is also considered to be a type or stage of kernicterus.

High bilirubin levels in a newborn’s blood can cause kernicterus, a kind of brain injury. Infants with severe, untreated jaundice are commonly linked to the illness. Athetoid cerebral palsy and hearing loss might develop. Kernicterus may cause dental and visual issues in addition to brain deficiencies. Kernicterus can be avoided with early diagnosis and treatment of jaundice.

Treatment is mostly used for kernicterus babies

Bilirubin can pass the thin tissue barrier separating the brain and blood in newborns with extremely high blood bilirubin levels (hyperbilirubinemia) (the blood-brain barrier).

The brain and spinal cord can suffer life-threatening damage from bilirubin.

Bilirubin encephalopathy is another name for brain damage brought on by excessive amounts of bilirubin.

What is kernicterus in medicine?

  • Many neonates’ skin will appear yellow because of jaundice. As a substance called bilirubin accumulates in the infant’s blood, it causes jaundice. At delivery, the infant’s liver must remove the bilirubin that the mother’s liver removed for the baby throughout pregnancy. In certain infants, the liver may not be mature enough to effectively eliminate bilirubin. The skin and whites of an infant’s eyes might appear yellow if there is an accumulation of too much bilirubin in the body. Jaundice is the name for this yellow coloration.
  • Kernicterus is a disorder that develops when severe jaundice is left untreated for an extended period of time. High bilirubin levels in a baby’s blood can cause kernicterus, a kind of brain injury. It can result in hearing loss and athetoid cerebral palsy. Further to eye and dental issues, kernicterus can occasionally result in cerebral difficulties. Kernicterus can be avoided with early jaundice diagnosis and treatment.

Market growth of kernicterus treatment market

 According to Data Bridge Market Research, at a CAGR of 2.50% from 2023 to 2030, the kernicterus treatments market, which is now valued at USD 2.86 billion in 2022, is anticipated to grow to USD 3.48 billion by 2030. The market reports compiled by Data Bridge Market Research also include in-depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework. These insights on market scenarios include market value, growth rate, segmentation, geographic coverage, and major players.

Fundamentals of kernicterus treatment market

  • Neonatal jaundice in babies poses serious health hazards if it is not treated or handled appropriately. Bilirubin meters are therefore highly sought after in both hospitals and child care facilities. Particularly, the expansion prospects of market participants have been influenced by advancements in neonatal hyperbilirubinemia detection. In affluent nations like the U.K., which has the potential for fast expansion, guidelines for handling neonates at risk are constantly evolving. It is noted that non-invasive transcutaneous bilirubin are strongly recommended to meet the demand for non-invasive bilirubin meters for infants and babies. The market for bilirubin meters is mostly driven by the rising use of high-tech equipment in developing countries.
  • The quick and efficient way to get rid of bilirubin that has already formed in the blood. The technique entails drawing out the baby’s blood, mostly the plasma, and replacing it with bilirubin-free citrate phosphate dextrose (CPD) preserved blood. When acute bilirubin encephalopathy symptoms are present and serum bilirubin levels are high despite attempts to decrease them, this disease is suggested. Serum bilirubin levels over 20–25 mg/dL are routinely treated with an exchange transfusion. Utilize an erythrocyte concentrate that is Rh-negative and matches your ABO type.

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