Untreated jaundice in infants can result in the rare but dangerous consequence of kernicterus. Excess bilirubin harms the brain or central nervous system, which is the cause of the condition.
Jaundice affects 60 to 80 percent of newborns worldwide. In wealthy countries, only 0.4 to 2.7 out of every 100,000 children get kernicterus or acute bilirubin encephalopathy. When bilirubin levels rise to this point, they spread to the brain and damage the CNS’s tissues. At the moment, “kernicterus” describes severe neurological damage brought on by jaundice. Nonetheless, any damage brought on by severe jaundice is also considered to be a type or stage of kernicterus.
High bilirubin levels in a newborn’s blood can cause kernicterus, a kind of brain injury. Infants with severe, untreated jaundice are commonly linked to the illness. Athetoid cerebral palsy and hearing loss might develop. Kernicterus may cause dental and visual issues in addition to brain deficiencies. Kernicterus can be avoided with early diagnosis and treatment of jaundice.
Bilirubin can pass the thin tissue barrier separating the brain and blood in newborns with extremely high blood bilirubin levels (hyperbilirubinemia) (the blood-brain barrier).
The brain and spinal cord can suffer life-threatening damage from bilirubin.
Bilirubin encephalopathy is another name for brain damage brought on by excessive amounts of bilirubin.
According to Data Bridge Market Research, at a CAGR of 2.50% from 2023 to 2030, the kernicterus treatments market, which is now valued at USD 2.86 billion in 2022, is anticipated to grow to USD 3.48 billion by 2030. The market reports compiled by Data Bridge Market Research also include in-depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework. These insights on market scenarios include market value, growth rate, segmentation, geographic coverage, and major players.
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